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Compare how my books approach first-line treatment for bipolar depression.

Your sources broadly agree on quetiapine and lurasidone but differ on lamotrigine:

  • Kaplan & Sadock lists quetiapine, lurasidone and lamotrigine as first-line monotherapy options. Kaplan & Sadock · p. 412
  • The Maudsley Guidelines are more cautious on lamotrigine monotherapy because of slow titration. Maudsley · p. 288
  • Your week 9 lecture notes flag quetiapine as the preferred answer for acute bipolar depression. Week 9 slides · p. 14

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